Microbiome-Dependent Protection Against <i>Corynebacterium bovis</i> -Associated Hyperkeratosis in Nude Mice ( <i>Mus musculus</i> )

can cause CAH as a monoinfection, that both host genetics and microbiome composition influence disease progression, and, together with prior work, support its role as the etiologic agent consistent with Koch's postulates. Identifying protective microbiome constituents may inform strategies to reduce disease burden in susceptible mice.

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-04-12
DOI
https://doi.org/10.64898/2026.04.11.716586
Primary Topic
Diphtheria, Corynebacterium, and Tetanus
Type
article
Field-Weighted Citation Impact
0.00
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article

Microbiome-Dependent Protection Against Corynebacterium bovis -Associated Hyperkeratosis in Nude Mice ( Mus musculus )

Rebecca Schmieley, Kate Fodor, Amanda C Ritter, Neil S Lipman
bioRxiv (Cold Spring Harbor Laboratory)
Diphtheria, Corynebacterium, and Tetanus
article

Microbiome-Dependent Protection Against Corynebacterium bovis -Associated Hyperkeratosis in Nude Mice ( Mus musculus )

Rebecca Schmieley, Kate Fodor, Amanda C Ritter, Neil S Lipman
article en

Abstract

can cause CAH as a monoinfection, that both host genetics and microbiome composition influence disease progression, and, together with prior work, support its role as the etiologic agent consistent with Koch's postulates. Identifying protective microbiome constituents may inform strategies to reduce disease burden in susceptible mice.

bioRxiv (Cold Spring Harbor Laboratory)
Memorial Sloan Kettering Cancer Center (US), Cornell University (US), Tri-Institutional PhD Program in Chemical Biology (US), Weill Cornell Medicine (US)
Openalex Percentile: Top 17%
Diphtheria, Corynebacterium, and Tetanus
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