Microbiome-Dependent Protection Against <i>Corynebacterium bovis</i> -Associated Hyperkeratosis in Nude Mice ( <i>Mus musculus</i> )
can cause CAH as a monoinfection, that both host genetics and microbiome composition influence disease progression, and, together with prior work, support its role as the etiologic agent consistent with Koch's postulates. Identifying protective microbiome constituents may inform strategies to reduce disease burden in susceptible mice.
Authors
- Rebecca Schmieley
- Kate Fodor
- Amanda C Ritter (ORCID: https://orcid.org/0000-0002-0966-5215)
- Neil S Lipman
Institutions
- Memorial Sloan Kettering Cancer Center (US)
- Cornell University (US)
- Tri-Institutional PhD Program in Chemical Biology (US)
- Weill Cornell Medicine (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-04-12
- DOI
- https://doi.org/10.64898/2026.04.11.716586
- Primary Topic
- Diphtheria, Corynebacterium, and Tetanus
- Type
- article
- Field-Weighted Citation Impact
- 0.00