Surgical Treatment of Tethered Cord Syndrome by Release of Filum Terminalis: A Review

Tethered cord syndrome (TCS) is a disease caused by pathological fixation of the spinal cord, most commonly due to a thickened filum terminale, postoperative adhesions, or congenital dysraphism. Progressive neurological, urological, and orthopedic manifestations result from chronic cord traction and impaired vascular supply. Surgical detethering remains the standard treatment, with the classic intradural sectioning of the filum terminale being the most widely used technique. Recent developments, however, include minimally invasive tubular and endoscopic approaches, spinal column shortening procedures for recurrent or complex cases, and extradural detethering strategies. Each technique aims to reduce cord tension while minimizing postoperative complications, particularly cerebrospinal fluid leakage and retethering. This review summarizes the anatomical background, pathophysiology, and operative strategies for TCS, highlighting current evidence, technical nuances, and limitations of emerging minimally invasive and alternative approaches.

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Publication Details

Journal
Children
Published
2026-04-12
DOI
https://doi.org/10.3390/children13040534
Primary Topic
Spinal Dysraphism and Malformations
Type
article
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0.00
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article

Surgical Treatment of Tethered Cord Syndrome by Release of Filum Terminalis: A Review

Marios Lampros, George Α. Alexiou, Flavio Giordano, Panagiota Zagorianakou et al.
Children
Spinal Dysraphism and Malformations
article

Surgical Treatment of Tethered Cord Syndrome by Release of Filum Terminalis: A Review

Marios Lampros, George Α. Alexiou, Flavio Giordano, Panagiota Zagorianakou, Spyridon Voulgaris
article en

Abstract

Tethered cord syndrome (TCS) is a disease caused by pathological fixation of the spinal cord, most commonly due to a thickened filum terminale, postoperative adhesions, or congenital dysraphism. Progressive neurological, urological, and orthopedic manifestations result from chronic cord traction and impaired vascular supply. Surgical detethering remains the standard treatment, with the classic intradural sectioning of the filum terminale being the most widely used technique. Recent developments, however, include minimally invasive tubular and endoscopic approaches, spinal column shortening procedures for recurrent or complex cases, and extradural detethering strategies. Each technique aims to reduce cord tension while minimizing postoperative complications, particularly cerebrospinal fluid leakage and retethering. This review summarizes the anatomical background, pathophysiology, and operative strategies for TCS, highlighting current evidence, technical nuances, and limitations of emerging minimally invasive and alternative approaches.

ChildrenVol. 13(4)
University of Ioannina (GR), Meyer Children's Hospital (IT), University Hospital of Ioannina (GR), University of Florence (IT)
Good health and well-being
Openalex Percentile: Top 24%
Spinal Dysraphism and Malformations
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