Ketogenic diet synergistic reprogramming of both host and microbiome promotes tissue regeneration
compromised the ability of the bacteria to promote tissue repair. Thus, host nutritional status drives tissue regeneration by synergistically rewiring host and microbial functions, providing new insights into how diet can be harnessed to regulate host physiology.
Authors
- Niki M. Moutsopoulos (ORCID: https://orcid.org/0000-0002-7365-6735)
- Verena M. Link (ORCID: https://orcid.org/0000-0002-3207-312X)
- Margery Smelkinson (ORCID: https://orcid.org/0000-0001-7777-5574)
- Benjamin Schwarz (ORCID: https://orcid.org/0000-0002-5894-953X)
- Michaël Otto (ORCID: https://orcid.org/0000-0002-2222-4115)
- Michael G. Constantinides (ORCID: https://orcid.org/0000-0003-4770-7751)
- Dan Corral (ORCID: https://orcid.org/0000-0002-0297-4349)
- L. Zheng
- Victor I. Band (ORCID: https://orcid.org/0000-0001-9288-0188)
- Andrew S. Burns
- Nicolas Bouladoux (ORCID: https://orcid.org/0000-0003-1593-671X)
- Liang Chi (ORCID: https://orcid.org/0000-0002-3769-4144)
- Nathan Brandes
- Motoyoshi Nagai (ORCID: https://orcid.org/0009-0002-0444-535X)
- Yasmine Belkaid
- Kathryn E. McCauley
- P Juliana Perez-Chaparro
Institutions
- National Institutes of Health (US)
- Scripps Institution of Oceanography (US)
- National Institute of Allergy and Infectious Diseases (US)
- Scripps (United States) (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-04-13
- DOI
- https://doi.org/10.64898/2026.04.11.717958
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Health and Human Services
- Office of Dietary Supplements
- Cancer Research Institute
- National Institutes of Health
- Japan Society for the Promotion of Science
- National Institute of Allergy and Infectious Diseases
- NHLBI Division of Intramural Research