Comparing CD8+ T cell ENV epitopes of two HLA class I alleles associated with different outcomes of HIV-1 infection with broadly neutralizing antibodies epitope targets discovered to date

T cell epitopes, that preferentially overlaps bNAb target sites, consistent with coordinated immune targeting between cellular and humoral arms of immunity.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-04-13
DOI
https://doi.org/10.3389/fimmu.2026.1786452
Primary Topic
HIV Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparing CD8+ T cell ENV epitopes of two HLA class I alleles associated with different outcomes of HIV-1 infection with broadly neutralizing antibodies epitope targets discovered to date

Robert W. Omange, Christina Daniuk, Ma Luo, Joshua Kimani et al.
Frontiers in Immunology
HIV Research and Treatment
article

Comparing CD8+ T cell ENV epitopes of two HLA class I alleles associated with different outcomes of HIV-1 infection with broadly neutralizing antibodies epitope targets discovered to date

Robert W. Omange, Christina Daniuk, Ma Luo, Joshua Kimani, Akhil Ramdoyal
article en

Abstract

T cell epitopes, that preferentially overlaps bNAb target sites, consistent with coordinated immune targeting between cellular and humoral arms of immunity.

Frontiers in ImmunologyVol. 17
University of Nairobi (KE), Public Health Agency of Canada (CA), Gilead Sciences (United States) (US), University of Manitoba (CA)
Good health and well-being
Openalex Percentile: Top 23%
HIV Research and Treatment
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