CavitoMod-UTMDNet: A Mechanistic Cavitation–Diffusion Framework for Ultrasound-Targeted Microbubble Destruction–Enhanced Liposomal Doxorubicin Delivery in Pancreatic Cancer

There were strong links between cavitation energy density and drug uptake and diffusion depth and therapeutic response as evidence that there is a mechanistic character to UTMD-enhanced actions. It will support the drug development in a better way. CavitoMod-UTMDNet is a combined strategy to maximize ultrasound-enhanced nanocarrier (nanoparticles) delivery using a physics-based reproducible plan to optimize ultrasound-enhanced nanocarrier delivery in PDAC that will see improvement in future translation to image-guided therapeutic strategies.

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Publication Details

Journal
Cancer Biotherapy and Radiopharmaceuticals
Published
2026-04-13
DOI
https://doi.org/10.1177/10849785261431195
Primary Topic
Ultrasound and Hyperthermia Applications
Type
article
Field-Weighted Citation Impact
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article

CavitoMod-UTMDNet: A Mechanistic Cavitation–Diffusion Framework for Ultrasound-Targeted Microbubble Destruction–Enhanced Liposomal Doxorubicin Delivery in Pancreatic Cancer

Yazeed Alashban, Mohammed Maray, Shouki A. Ebad, Nujud Aloshban et al.
Cancer Biotherapy and Radiopharmaceuticals
Ultrasound and Hyperthermia Applications
article

CavitoMod-UTMDNet: A Mechanistic Cavitation–Diffusion Framework for Ultrasound-Targeted Microbubble Destruction–Enhanced Liposomal Doxorubicin Delivery in Pancreatic Cancer

Yazeed Alashban, Mohammed Maray, Shouki A. Ebad, Nujud Aloshban, Ghada Moh Samir Elhessewi, Rana Alabdan, Hanadi Alkhudhayr, Ali M. Al-Sharafi
article en

Abstract

There were strong links between cavitation energy density and drug uptake and diffusion depth and therapeutic response as evidence that there is a mechanistic character to UTMD-enhanced actions. It will support the drug development in a better way. CavitoMod-UTMDNet is a combined strategy to maximize ultrasound-enhanced nanocarrier (nanoparticles) delivery using a physics-based reproducible plan to optimize ultrasound-enhanced nanocarrier delivery in PDAC that will see improvement in future translation to image-guided therapeutic strategies.

Cancer Biotherapy and Radiopharmaceuticals
Princess Nourah bint Abdulrahman University (SA), Northern Border University (SA), King Abdulaziz University (SA), Majmaah University (SA), Imam Mohammad ibn Saud Islamic University (SA), King Saud University (SA), University of Bisha (SA), King Khalid University (SA)
No poverty
Openalex Percentile: Top 25%
Ultrasound and Hyperthermia Applications
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