Neutralization Kinetics and Transport Define the Dermal Decontamination Window for Warfare and Industrial Toxicants

(>8), where rapid bulk neutralization renders surface-based interventions progressively less effective. The framework identifies a critical decontamination window during which the applied decontaminant neutralizes the agent faster than it can enter the bloodstream, thereby minimizing systemic exposure. Implemented as open-source Python software, this tool can help emergency responders and regulatory agencies predict decontamination windows for chemical warfare agents and industrial toxicants.

Authors

Institutions

Publication Details

Journal
Chemical Research in Toxicology
Published
2026-04-12
DOI
https://doi.org/10.1021/acs.chemrestox.5c00540
Primary Topic
Advancements in Transdermal Drug Delivery
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Neutralization Kinetics and Transport Define the Dermal Decontamination Window for Warfare and Industrial Toxicants

Laurent Simon, Ishita Kulkarni
Chemical Research in Toxicology
Advancements in Transdermal Drug Delivery
article

Neutralization Kinetics and Transport Define the Dermal Decontamination Window for Warfare and Industrial Toxicants

Laurent Simon, Ishita Kulkarni
article en

Abstract

(>8), where rapid bulk neutralization renders surface-based interventions progressively less effective. The framework identifies a critical decontamination window during which the applied decontaminant neutralizes the agent faster than it can enter the bloodstream, thereby minimizing systemic exposure. Implemented as open-source Python software, this tool can help emergency responders and regulatory agencies predict decontamination windows for chemical warfare agents and industrial toxicants.

Chemical Research in Toxicology
New Jersey Institute of Technology (US), Otto-von-Guericke-Universität Magdeburg (DE)
Army Research Office
Openalex Percentile: Top 20%
Advancements in Transdermal Drug Delivery
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.