Early diagnosis and risk groups: comorbidities in newly diagnosed adults with HIV in Turkey

OBJECTIVES: This study aimed to identify factors contributing to the early diagnosis of HIV in Turkey, with a particular focus on high-risk populations, comorbid conditions, and temporal trends. It also evaluated whether initial clinical findings could inform the expansion of screening strategies. METHODS: A retrospective analysis was conducted on 1,703 individuals living with human immunodeficiency virus (HIV) who attended our clinic between 2004 and 2023. Patients were grouped into five-year intervals and assessed based on demographic characteristics, reasons for testing, and reported comorbidities. RESULTS: Among the participants, 90.3% were males, with a mean age of 36.6 years. Of those who disclosed their sexual orientation, 46.8% identified as heterosexual. Common comorbidities included anal region disorders, cardiovascular and pulmonary diseases, diabetes, and syphilis. HBsAg positivity was 5%, and anti-HCV positivity was 0.86%. Nearly half of the patients (48.6%) were asymptomatic at the time of diagnosis. Physician-initiated testing and routine screenings played a significant role in early detection. CONCLUSION: Early diagnosis of HIV is essential for reducing transmission and improving patient outcomes. Screening programmes should be expanded to include not only high-risk groups but also sexually active individuals presenting with relevant clinical symptoms. Public health efforts must address stigma and improve access to HIV testing to optimize early detection and treatment.