MiR-21 Is a Novel Diagnostic and Prognostic Circulating Biomarker in Pleural Mesothelioma
Our findings highlight that circulating miR-21 is a potential non-invasive biomarker with both diagnostic and independent prognostic value in pleural mesothelioma and outperforms SMRP in multivariable survival analysis. Further research is warranted to validate its role in the biology of this disease and to assess its correlation with outcome and treatment responses.
Authors
- Mir Alireza Hoda (ORCID: https://orcid.org/0000-0002-7088-8768)
- Elisabeth Lang (ORCID: https://orcid.org/0000-0001-5748-1376)
- Balázs Hegedűs (ORCID: https://orcid.org/0000-0002-4341-4153)
- Natalie Baldes (ORCID: https://orcid.org/0000-0002-8719-2206)
- Michael Grusch (ORCID: https://orcid.org/0000-0001-5486-9340)
- Karin Schelch (ORCID: https://orcid.org/0000-0001-8742-1737)
- Marko Jakopović (ORCID: https://orcid.org/0000-0002-4815-7512)
- Servet Bölükbas (ORCID: https://orcid.org/0000-0001-8275-5957)
- Balázs Döme (ORCID: https://orcid.org/0000-0001-8799-8624)
- Thomas Klikovits (ORCID: https://orcid.org/0000-0003-1012-0404)
- Yawen Dong (ORCID: https://orcid.org/0000-0002-3631-1228)
- Katharina Sinn (ORCID: https://orcid.org/0000-0002-3936-2354)
- Viktória László (ORCID: https://orcid.org/0000-0002-6567-3965)
- Berta Mosleh (ORCID: https://orcid.org/0009-0005-9805-9733)
- Clemens Aigner (ORCID: https://orcid.org/0000-0002-7787-991X)
- S C‐H KAO
Institutions
- Semmelweis University (HU)
- The University of Sydney (AU)
- University Hospital Centre Zagreb (HR)
- Comprehensive Cancer Center Vienna (AT)
- National Institute of Oncology (HU)
- Karl Landsteiner Society (AT)
- Országos Korányi Tbc és Pulmonológiai Intézet (HU)
- University of Duisburg-Essen (DE)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Diagnostics
- Published
- 2026-04-11
- DOI
- https://doi.org/10.3390/diagnostics16081142
- Primary Topic
- Occupational and environmental lung diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Austrian Science Fund