Correlation Between Epicardial Adipose Tissue and PET Cardiac Perfusion: A Systematic Review

: This systematic review seems to suggest a potential association between increased EAT and impaired myocardial perfusion, as assessed by PET. However, significant methodological heterogeneity across the available studies-including differences in EAT quantification, PET protocols, and tracer selection-limits the strength of this conclusion. Standardized imaging protocols and larger, prospective, multicenter studies are required to validate this relationship, determine its incremental prognostic value, and evaluate its potential for integration into routine clinical risk stratification pathways.

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Publication Details

Journal
Medical Sciences
Published
2026-04-11
DOI
https://doi.org/10.3390/medsci14020194
Primary Topic
Cardiovascular Disease and Adiposity
Type
article
Field-Weighted Citation Impact
0.00
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article

Correlation Between Epicardial Adipose Tissue and PET Cardiac Perfusion: A Systematic Review

Francesco Dondi, E Vizzardi, Luca Camoni, Gian Luca Viganò et al.
Medical Sciences
Cardiovascular Disease and Adiposity
article

Correlation Between Epicardial Adipose Tissue and PET Cardiac Perfusion: A Systematic Review

Francesco Dondi, E Vizzardi, Luca Camoni, Gian Luca Viganò, M. Bertoli, Roberto Rinaldi, Michela Cossandi, Pietro Bellini, Francesco Bertagna
article en

Abstract

: This systematic review seems to suggest a potential association between increased EAT and impaired myocardial perfusion, as assessed by PET. However, significant methodological heterogeneity across the available studies-including differences in EAT quantification, PET protocols, and tracer selection-limits the strength of this conclusion. Standardized imaging protocols and larger, prospective, multicenter studies are required to validate this relationship, determine its incremental prognostic value, and evaluate its potential for integration into routine clinical risk stratification pathways.

Medical SciencesVol. 14(2)
Surgical Specialties (Canada) (CA), Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT), University of Brescia (IT)
Good health and well-being
Openalex Percentile: Top 20%
Cardiovascular Disease and Adiposity
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