The Role of Systemic Inflammation in Age-Related Macular Degeneration Subtypes: Exploring Novel Biomarkers

: Patients with wet AMD exhibit a more pronounced systemic inflammatory profile than both dry AMD patients and healthy controls. These findings support the hypothesis that systemic inflammation may contribute to AMD pathogenesis. Geographic atrophy in dry AMD may also be associated with additional hematologic alterations, whereas treatment response in wet AMD is not reflected in systemic markers.

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Publication Details

Journal
Diagnostics
Published
2026-04-11
DOI
https://doi.org/10.3390/diagnostics16081144
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

The Role of Systemic Inflammation in Age-Related Macular Degeneration Subtypes: Exploring Novel Biomarkers

Barbaros Hayrettin Unlu, Ceren Durmaz Engin, Taylan Öztürk
Diagnostics
Inflammatory Biomarkers in Disease Prognosis
article

The Role of Systemic Inflammation in Age-Related Macular Degeneration Subtypes: Exploring Novel Biomarkers

Barbaros Hayrettin Unlu, Ceren Durmaz Engin, Taylan Öztürk
article en

Abstract

: Patients with wet AMD exhibit a more pronounced systemic inflammatory profile than both dry AMD patients and healthy controls. These findings support the hypothesis that systemic inflammation may contribute to AMD pathogenesis. Geographic atrophy in dry AMD may also be associated with additional hematologic alterations, whereas treatment response in wet AMD is not reflected in systemic markers.

DiagnosticsVol. 16(8)
Izmir University (TR), Sivas State Hospital (TR)
Good health and well-being
Openalex Percentile: Top 26%
Inflammatory Biomarkers in Disease Prognosis
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