Diffuse endobronchial polyposis associated with chlorosilane inhalation

INTRODUCTION: Chlorosilane is widely used in modern industry. The health effect in humans after chlorosilane exposure is still unclear. CASE SUMMARY: retention with difficulty weaning. Bronchoscopy showed diffuse endobronchial polyposis two months after exposure. IMAGES: Serial radiographs, bronchoscopy images demonstrated the course of severe respiratory injury and an uncommon sequalae of diffuse inflammatory endobronchial polyps. DISCUSSION: The pathogenesis of polyp formation may be associated with prolonged inflammation. Interventional bronchoscopy was used to remove the polyps. Corticosteroids may be considered, but there is the risk of superimposed infection. CONCLUSION: Chlorosilane inhalation could induce severe lung damage. Multiple endobronchial polyps may be a severe sequela contributing to difficulty weaning.

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Publication Details

Journal
Clinical Toxicology
Published
2026-04-13
DOI
https://doi.org/10.1080/15563650.2025.2591337
Primary Topic
Occupational exposure and asthma
Type
article
Field-Weighted Citation Impact
0.00
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article

Diffuse endobronchial polyposis associated with chlorosilane inhalation

Zewu Qiu, Xigang Zhang, Lili Bai, Chengcheng Ji et al.
Clinical Toxicology
Occupational exposure and asthma
article

Diffuse endobronchial polyposis associated with chlorosilane inhalation

Zewu Qiu, Xigang Zhang, Lili Bai, Chengcheng Ji, Xiaobo Peng
article en

Abstract

INTRODUCTION: Chlorosilane is widely used in modern industry. The health effect in humans after chlorosilane exposure is still unclear. CASE SUMMARY: retention with difficulty weaning. Bronchoscopy showed diffuse endobronchial polyposis two months after exposure. IMAGES: Serial radiographs, bronchoscopy images demonstrated the course of severe respiratory injury and an uncommon sequalae of diffuse inflammatory endobronchial polyps. DISCUSSION: The pathogenesis of polyp formation may be associated with prolonged inflammation. Interventional bronchoscopy was used to remove the polyps. Corticosteroids may be considered, but there is the risk of superimposed infection. CONCLUSION: Chlorosilane inhalation could induce severe lung damage. Multiple endobronchial polyps may be a severe sequela contributing to difficulty weaning.

Clinical Toxicology
Chinese General Hospital College of Nursing and Liberal Arts (PH)
Good health and well-being
Openalex Percentile: Top 21%
Occupational exposure and asthma
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