Efficacy and safety of 2–4 mg brexpiprazole in the management of schizophrenia: A systematic review and meta‐analysis

= 0.0002). The most usual extrapyramidal symptom was akathisia. Brexpiprazole 2-4 mg showed significant improvements in PANSS and CGI-S scores, with a lower risk of treatment discontinuation. These findings support its efficacy and tolerability in managing schizophrenia.

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Publication Details

Journal
Psychiatry and Clinical Neurosciences Reports
Published
2026-04-12
DOI
https://doi.org/10.1002/pcn5.70332
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and safety of 2–4 mg brexpiprazole in the management of schizophrenia: A systematic review and meta‐analysis

Muhammad Bilal Akbar, Abdul Haseeb Mohammed, Sadikun Nabi, Saliha Saad et al.
Psychiatry and Clinical Neurosciences Reports
Schizophrenia research and treatment
article

Efficacy and safety of 2–4 mg brexpiprazole in the management of schizophrenia: A systematic review and meta‐analysis

Muhammad Bilal Akbar, Abdul Haseeb Mohammed, Sadikun Nabi, Saliha Saad, Ismailova Rushana Nurbekovna, Hiba Manaf, Sher Bano, Aashan Ahmad, SIDRA HARISS, Farah Saleh, Noor Fatima, Raouf Khan, Zainab Salahuddin, Laiba Ajmal
article en

Abstract

= 0.0002). The most usual extrapyramidal symptom was akathisia. Brexpiprazole 2-4 mg showed significant improvements in PANSS and CGI-S scores, with a lower risk of treatment discontinuation. These findings support its efficacy and tolerability in managing schizophrenia.

Psychiatry and Clinical Neurosciences ReportsVol. 5(2)
University of Jordan (JO), Jordan University of Science and Technology (JO), Comilla Medical College (BD), Jordan Hospital (JO), Combined Military Hospital (PK), Montgomery High School (US), Tallaght University Hospital (IE), Shaheed Zulfiqar Ali Bhutto Institute of Science and Technology (PK), Shifa Tameer-e-Millat University (PK), Thumbay Group (United Arab Emirates) (AE), Tashkent Pediatric Medical Institute (UZ), Pakistan Institute of Medical Sciences (PK), Westminster International University in Tashkent (UZ)
Good health and well-being
Openalex Percentile: Top 17%
Schizophrenia research and treatment
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