The <i>gac</i> system integrates physical and chemical cues to promote plant root attachment

system activates cyclic di-GMP-mediated attachment programs that drive the transition from planktonic to sessile behavior required for root association. We build on this model to show that manipulating flagellar surface sensing enhances the competitive fitness of Pf-5 in the presence of a synthetic bacterial community, suggesting a strategy to improve the competitive fitness of beneficial microbes on crops. These findings establish a mechanistic framework linking surface sensing, global regulation, and root attachment in a beneficial rhizobacterium.

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-04-12
DOI
https://doi.org/10.64898/2026.04.10.717875
Primary Topic
Bacterial biofilms and quorum sensing
Type
article
Field-Weighted Citation Impact
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article

The gac system integrates physical and chemical cues to promote plant root attachment

Guy Sobol, David M. Hershey
bioRxiv (Cold Spring Harbor Laboratory)
Bacterial biofilms and quorum sensing
article

The gac system integrates physical and chemical cues to promote plant root attachment

Guy Sobol, David M. Hershey
article en

Abstract

system activates cyclic di-GMP-mediated attachment programs that drive the transition from planktonic to sessile behavior required for root association. We build on this model to show that manipulating flagellar surface sensing enhances the competitive fitness of Pf-5 in the presence of a synthetic bacterial community, suggesting a strategy to improve the competitive fitness of beneficial microbes on crops. These findings establish a mechanistic framework linking surface sensing, global regulation, and root attachment in a beneficial rhizobacterium.

bioRxiv (Cold Spring Harbor Laboratory)
University of Wisconsin–Madison (US)
Openalex Percentile: Top 20%
Bacterial biofilms and quorum sensing
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