More than a symptom: itch as an independent clinical contributor in atopic dermatitis - a global-scale study on 15,223 patients
This international study of 15,223 atopic dermatitis patients across 27 countries reveals that severe pruritus significantly impairs quality of life, affecting daily activities, professional careers, and social relationships. Using validated tools like ABS-A, SOL, and PUSH-D, it underscores pruritus as a key independent factor in disease burden, highlighting the urgent need for its systematic evaluation and targeted management in clinical practice.
Authors
- Bruno Halioua (ORCID: https://orcid.org/0000-0002-0823-6750)
- Therdpong Tempark (ORCID: https://orcid.org/0000-0001-5645-2135)
- Charbel Skayem (ORCID: https://orcid.org/0000-0002-4498-0683)
- Wendy Smith Begolka (ORCID: https://orcid.org/0000-0001-6107-5282)
- Delphine Kérob (ORCID: https://orcid.org/0000-0003-2816-4261)
- Martin Steinhoff (ORCID: https://orcid.org/0000-0002-7090-2187)
- C. Taïeb (ORCID: https://orcid.org/0000-0002-5142-2479)
- Nabil Kerrouche
- Roberto Takaoka (ORCID: https://orcid.org/0000-0003-0952-2641)
- Stéphanie Mérhand
- Flávia Pretti Aslanian
- Julien Sénéschal (ORCID: https://orcid.org/0000-0003-1139-0908)
- África Luca de Tena Smith
- Chaoying Gu (ORCID: https://orcid.org/0009-0009-9266-6785)
- Abraham Getachew
- Ann’Laure Demessant Flavigny
- Shulamit Burstein
- Cita Rosita Sigit Prakoeswa
- Alexander Stratigos
- Thomas Luger
- Laurent Misery (ORCID: https://orcid.org/0000-0001-8088-7059)
- Roni Dodiuk-Gad
- Caroline Le Floc’h
- Jerry Tan
- Jonathan I Silverberg (ORCID: https://orcid.org/0000-0003-3686-7805)
Institutions
- Western University (CA)
- Centre National de la Recherche Scientifique (FR)
- Université de Bordeaux (FR)
- Universidade de São Paulo (BR)
- George Washington University (US)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- National and Kapodistrian University of Athens (GR)
- Universitas Airlangga (ID)
- Fudan University (CN)
- Université Paris-Saclay (FR)
- King Chulalongkorn Memorial Hospital (TH)
- Assistance Publique – Hôpitaux de Paris (FR)
- Windsor Clinical Research (CA)
- University Hospital Münster (DE)
- Nuffield Health (GB)
- Hôpital Saint-André (FR)
- Rappaport Family Institute for Research in the Medical Sciences (IL)
- Andreas Sygros Hospital (GR)
- Asociación Española de Urología (ES)
- National Clinical Research (US)
- Délégation Paris 6 (FR)
- Centre Hospitalier Régional Universitaire de Brest (FR)
- National Eczema Association (US)
- Hôpital Ambroise-Paré (FR)
- Hamad bin Khalifa University (QA)
- The Korean Atopic Dermatitis Association (KR)
- Parkside Hospital (GB)
- St. Paul's Hospital Millennium Medical College (ET)
- Huashan Hospital (CN)
- Hospital São Paulo (BR)
- Health & Life (Taiwan) (TW)
- The Patients Association (GB)
- Hamad Medical Corporation (QA)
- La Roche College (US)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2026-04-10
- DOI
- https://doi.org/10.1093/bjd/ljag142
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00