Application of Polymers in Advanced Materials for Enamel and Dentine Remineralization

Dental caries, the most common oral disease with a worldwide burden, causes structural damage to enamel and dentine. Considering the limitations of conventional restorative approaches and the dynamic nature of caries, biomimetic remineralization strategies offer a promising alternative for restoring tooth structure. Central to many of these strategies is the use of polymers to emulate the role of macromolecular templates in natural mineralization processes. This review summarizes the polymers applied for biomimetic mineralization of enamel and dentine according to their primary functions. Furthermore, perspectives on the trends and challenges for future research on polymeric biomaterials for enamel and dentine repair are also presented.

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Publication Details

Journal
ACS Biomaterials Science & Engineering
Published
2026-04-13
DOI
https://doi.org/10.1021/acsbiomaterials.5c02188
Primary Topic
Bone and Dental Protein Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Application of Polymers in Advanced Materials for Enamel and Dentine Remineralization

Zichen Wu, Hai Ming Wong, Yanchuan Guo, Quanli Li et al.
ACS Biomaterials Science & Engineering
Bone and Dental Protein Studies
article

Application of Polymers in Advanced Materials for Enamel and Dentine Remineralization

Zichen Wu, Hai Ming Wong, Yanchuan Guo, Quanli Li, Jingwen Wu, Le Zhang
article en

Abstract

Dental caries, the most common oral disease with a worldwide burden, causes structural damage to enamel and dentine. Considering the limitations of conventional restorative approaches and the dynamic nature of caries, biomimetic remineralization strategies offer a promising alternative for restoring tooth structure. Central to many of these strategies is the use of polymers to emulate the role of macromolecular templates in natural mineralization processes. This review summarizes the polymers applied for biomimetic mineralization of enamel and dentine according to their primary functions. Furthermore, perspectives on the trends and challenges for future research on polymeric biomaterials for enamel and dentine repair are also presented.

ACS Biomaterials Science & EngineeringVol. 12(5)
Anhui Medical University (CN), Chinese Academy of Sciences (CN), Longgang Central Hospital (CN), Technical Institute of Physics and Chemistry (CN), University of Chinese Academy of Sciences (CN), University of Hong Kong (HK)
National Natural Science Foundation of China, Research Grants Council, University Grants Committee
Openalex Percentile: Top 31%
Bone and Dental Protein Studies
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