Multiplexed Isothermal Amplification Assay for the Detection of <i>Plasmodium falciparum</i> and <i>Trichomonas vaginalis</i> in Urine

copies/μL in processed human urine, demonstrating clinically relevant sensitivity for noninvasive, multiplexed detection. However, use with a neat urine sample requires a processing step that may limit POC use. In our clinics in Kenya, we process samples nearby, and a fast molecular test that does not require thermocycling, with a turnaround time within the span of a typical prenatal visit, will positively impact our patients.

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Publication Details

Journal
ACS Omega
Published
2026-04-13
DOI
https://doi.org/10.1021/acsomega.5c12022
Primary Topic
Reproductive tract infections research
Type
article
Field-Weighted Citation Impact
0.00

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article

Multiplexed Isothermal Amplification Assay for the Detection of Plasmodium falciparum and Trichomonas vaginalis in Urine

Catherine M. Klapperich, Jesse Gitaka, Berit Schaus, Srinivasa Raju Lolabattu et al.
ACS Omega
Reproductive tract infections research
article

Multiplexed Isothermal Amplification Assay for the Detection of Plasmodium falciparum and Trichomonas vaginalis in Urine

Catherine M. Klapperich, Jesse Gitaka, Berit Schaus, Srinivasa Raju Lolabattu, Joshua Dupaty, Clement Shiluli
article en

Abstract

copies/μL in processed human urine, demonstrating clinically relevant sensitivity for noninvasive, multiplexed detection. However, use with a neat urine sample requires a processing step that may limit POC use. In our clinics in Kenya, we process samples nearby, and a fast molecular test that does not require thermocycling, with a turnaround time within the span of a typical prenatal visit, will positively impact our patients.

ACS OmegaVol. 11(16)
Mount Kenya University (KE), National Centre for Infectious Diseases (SG)
Boston University
Zero hunger
Openalex Percentile: Top 27%
Reproductive tract infections research
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