Immune Microenvironment and Genetic Signatures of End-Stage Renal Disease and Their Association with Sepsis: Insights from Public Transcriptomic Data and a Multicenter Clinical Cohort
: ESRD shares similar immune microenvironmental features and genetic signatures with sepsis. These shared characteristics may contribute to the greater sepsis severity and poorer outcomes observed in patients with ESRD.
Authors
- Ming-Cheng Chan (ORCID: https://orcid.org/0000-0002-4407-8841)
- Chung‐Kan Peng (ORCID: https://orcid.org/0000-0001-5696-2557)
- Yi‐Cheng Shen (ORCID: https://orcid.org/0000-0001-5459-5378)
- Biing‐Ru Wu (ORCID: https://orcid.org/0000-0002-2824-4387)
- Sheng‐Huei Wang (ORCID: https://orcid.org/0000-0002-5267-0618)
- CHAU-CHYUN SHEU
- Shih‐Ming Huang (ORCID: https://orcid.org/0000-0001-9305-921X)
- Wei-Hsuan Huang
- K. M. Yang
- Jia-Yih Feng
- Chia-Min Chen
Institutions
- National Yang Ming Chiao Tung University (TW)
- Kaohsiung Medical University (TW)
- National Chung Hsing University (TW)
- China Medical University (TW)
- Kaohsiung Medical University Chung-Ho Memorial Hospital (TW)
- Taipei Veterans General Hospital (TW)
- Taichung Veterans General Hospital (TW)
- National Defense University (TW)
- China Medical University Hospital (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- Biomedicines
- Published
- 2026-04-13
- DOI
- https://doi.org/10.3390/biomedicines14040885
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tri-Service General Hospital