Initial Denosumab Versus Sequential Bisphosphonate-to-Denosumab for Prevention of Skeletal-Related Events in Breast Cancer with Bone Metastases: A Retrospective, Single-Center Study
Initial denosumab was associated with fewer and delayed SREs compared with sequential bisphosphonate-to-denosumab therapy, supporting early denosumab initiation as a potentially preferable BTA strategy. Prospective studies are warranted to confirm these findings.
Authors
- Yan Zhao (ORCID: https://orcid.org/0000-0002-6148-5908)
- Yizhao Xie
- Bo Yu (ORCID: https://orcid.org/0009-0008-0286-7480)
- Wanjing Feng
- Yu Shi (ORCID: https://orcid.org/0000-0001-6471-6241)
- Jun Cao
Institutions
- Fudan University Shanghai Cancer Center (CN)
Publication Details
- Journal
- Cancers
- Published
- 2026-04-12
- DOI
- https://doi.org/10.3390/cancers18081222
- Primary Topic
- Bone health and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00