The Cortical Contributions to Turning Performance Through Muscle Synergies in Parkinson’s Disease: A Mediation Study
< 0.03). This work establishes how muscle synergy complexity significantly mediates the relationship between cortical connectivity and turning performance in PD. Our findings provide evidence of a cortical-neuromuscular-behavioral pathway underlying turning deficits, highlighting coordination as a key target for neurorehabilitation.
Authors
- Mirabel Ewura Esi Acquah (ORCID: https://orcid.org/0009-0008-6375-0681)
- W L Chen
- Zheng Wang (ORCID: https://orcid.org/0000-0003-4873-505X)
- Dongyun Gu
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai Ninth People's Hospital (CN)
- Huashan Hospital (CN)
- Shanghai Huangpu District Central Hospital (CN)
Publication Details
- Journal
- Bioengineering
- Published
- 2026-04-13
- DOI
- https://doi.org/10.3390/bioengineering13040453
- Primary Topic
- Motor Control and Adaptation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Shanghai Jiao Tong University
- National Key Research and Development Program of China