Integrative Bioinformatic Analysis Identifies Key Genes Driving Breast Cancer Brain Metastasis
This study identifies a unique molecular profile of BCBM characterized by cell cycle dysregulation, metabolic reprogramming, and immune microenvironment alterations. The brain-specific expression patterns of these hub genes represent potential biomarkers for BCBM risk assessment and novel therapeutic targets, providing a basis for precision medicine development.
Authors
- Yueh‐Hsun Lu (ORCID: https://orcid.org/0000-0002-2471-8602)
- Wei-Yi Ting
Institutions
- Taipei Medical University-Shuang Ho Hospital (TW)
- Taipei Medical University (TW)
Publication Details
- Journal
- Diagnostics
- Published
- 2026-04-13
- DOI
- https://doi.org/10.3390/diagnostics16081149
- Primary Topic
- 14-3-3 protein interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00