Four New Glycosides From <i>Siraitia grosvenorii</i> : Isolation, Structural Identification, and Their Anti‐Inflammatory Activities
Four new compounds, including two phenylethanoid glycosides (1-2) and two alkyl glycosides (3-4), as well as five known ones (5-9), were isolated from the 95% ethanol extract of Siraitia grosvenorii after purification using D-101 macroporous resin and subsequent elution with 20% ethanol. Among the known compounds, compounds 6, 7, and 9 were obtained from S. grosvenorii for the first time. The in vitro anti-inflammatory activity assay showed that at a concentration of 10 µM, compounds 1, 2, 4-6, and 9 had certain inhibitory effects on LPS-induced NO production in RAW264.7 cells.
Authors
- Yulu Wei
- Haiying Jiang (ORCID: https://orcid.org/0000-0001-8160-9480)
- Xiaoling Tan (ORCID: https://orcid.org/0000-0003-4909-3597)
- Jingru Song
- Fenglai Lu (ORCID: https://orcid.org/0000-0002-8114-1766)
- Wan‐Zhen Cai
- Xiao‐Hua Jiang
- Xiao‐Jie Yan
Institutions
- Guangxi University (CN)
- Guilin Medical University (CN)
- Guangxi Normal University (CN)
- Guangxi Institute of Botany (CN)
- Guangxi University of Chinese Medicine (CN)
Publication Details
- Journal
- Chemistry & Biodiversity
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1002/cbdv.202503642
- Primary Topic
- Biochemical Analysis and Sensing Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China