A unifying theory of brain signaling and its possible role in acquired chronic disease

dysregulates these signals to cause chronic symptoms (e.g., low temperature, impaired movement, memory loss, reduced glomerular filtration rate). If confirmed, this view of chronic symptoms as a dysregulation of normal process via neuronal adaptation, has profound implications. It could explain Parkinson's, Alzheimer's and chronic kidney disease, among others, and, as it may be possible to downregulate CRFR2, could reverse the signs and symptoms of such diseases.