Computational toxicity profiling of the UV stabilizer UV-328 against the human brain enzyme acetylcholinesterase

predictions of ADMET and CNS penetration also indicated that UV-328 has physicochemical characteristics that are consistent with blood-brain barrier permeation. Collectively, these results suggest that a relatively stable interaction between UV-328 and acetylcholinesterase is possible, which supports the hypothesis of potential neurotoxic relevance of the compound and warrants further investigation. Reuslts are hypothetical and require experimrntal validation.