Factors associated with methotrexate-related gastrointestinal intolerance and toxicity in rheumatoid arthritis and psoriatic arthritis.
MTX-related GIAE are frequently and largely driven by metabolic comorbidities, lifestyle exposures, sex and baseline ALT. These routinely available parameters allow early identification of high-risk patients and may guide personalized MTX initiation and monitoring strategies.
Authors
- Paulo Pereira (ORCID: https://orcid.org/0000-0003-4819-2112)
- Carla Campinho Ferreira (ORCID: https://orcid.org/0000-0003-3239-2400)
- Hugo Gonçalves (ORCID: https://orcid.org/0000-0003-1700-2179)
- Mariana Pinheiro
- Inês Borges
- Emanuel Costa
Institutions
- Unidade Hospitalar de Bragança (PT)
- University of Minho (PT)
Publication Details
- Journal
- PubMed
- Published
- 2026-04-12
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00