Bronchial Mucosal Abnormalities in Idiopathic Subglottic Stenosis

OBJECTIVES: Investigate synchronous lower airway findings during bronchoscopy in idiopathic subglottic stenosis (iSGS). METHODS: Retrospective analysis of bronchoscopic images from adult iSGS patients (January 2018-June 2021). Images were reviewed for pits, depressions, nodules, and striations distal to the cricotracheal junction. RESULTS: /FVC < 0.7; two had asthma, one COPD, and one no obstructive diagnosis; none were smokers. CONCLUSION: Bronchial mucosal abnormalities are prevalent in iSGS and may indicate distal airway involvement. Routine flexible bronchoscopy should be considered during evaluation and surveillance.

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Publication Details

Journal
The Laryngoscope
Published
2026-04-12
DOI
https://doi.org/10.1002/lary.70543
Primary Topic
Tracheal and airway disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Bronchial Mucosal Abnormalities in Idiopathic Subglottic Stenosis

J. Scott Ferguson, Sydney Ring, Seth H. Dailey, Tessa C. Griffin et al.
The Laryngoscope
Tracheal and airway disorders
article

Bronchial Mucosal Abnormalities in Idiopathic Subglottic Stenosis

J. Scott Ferguson, Sydney Ring, Seth H. Dailey, Tessa C. Griffin, Andrew J. Bowen
article en

Abstract

OBJECTIVES: Investigate synchronous lower airway findings during bronchoscopy in idiopathic subglottic stenosis (iSGS). METHODS: Retrospective analysis of bronchoscopic images from adult iSGS patients (January 2018-June 2021). Images were reviewed for pits, depressions, nodules, and striations distal to the cricotracheal junction. RESULTS: /FVC < 0.7; two had asthma, one COPD, and one no obstructive diagnosis; none were smokers. CONCLUSION: Bronchial mucosal abnormalities are prevalent in iSGS and may indicate distal airway involvement. Routine flexible bronchoscopy should be considered during evaluation and surveillance.

The Laryngoscope
MetroHealth (US), Mayo Clinic (US), University of Wisconsin–Madison (US), WinnMed (US), Pulmonary and Allergy Associates (US)
Openalex Percentile: Top 19%
Tracheal and airway disorders
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