Giant epidermoid cyst of the floor of mouth masquerading as a foregut duplication cyst: a case report and review of the literature

Epidermoid cysts are benign lesions composed of an epithelial lining filled with keratinous debris. The absence of skin appendages distinguishes them from true dermoid cysts. While they may occur in various anatomical locations, they rarely exceed the 5-cm threshold used to define 'giant' lesions. We report a unique case of a giant epidermoid cyst arising from the floor of the mouth, reaching a maximum diameter of 10 cm and initially mimicking a foregut duplication cyst on imaging. We describe its clinical presentation, radiological evaluation, surgical management, and histopathological diagnosis, alongside a review of the current literature.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2026-04-01
DOI
https://doi.org/10.1093/jscr/rjag198
Primary Topic
Teratomas and Epidermoid Cysts
Type
article
Field-Weighted Citation Impact
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article

Giant epidermoid cyst of the floor of mouth masquerading as a foregut duplication cyst: a case report and review of the literature

Hany Hashesh, Satnam Singh Rehal, Sundarraj Lakshmiah, Andre Alleyne
Journal of Surgical Case Reports
Teratomas and Epidermoid Cysts
article

Giant epidermoid cyst of the floor of mouth masquerading as a foregut duplication cyst: a case report and review of the literature

Hany Hashesh, Satnam Singh Rehal, Sundarraj Lakshmiah, Andre Alleyne
article en

Abstract

Epidermoid cysts are benign lesions composed of an epithelial lining filled with keratinous debris. The absence of skin appendages distinguishes them from true dermoid cysts. While they may occur in various anatomical locations, they rarely exceed the 5-cm threshold used to define 'giant' lesions. We report a unique case of a giant epidermoid cyst arising from the floor of the mouth, reaching a maximum diameter of 10 cm and initially mimicking a foregut duplication cyst on imaging. We describe its clinical presentation, radiological evaluation, surgical management, and histopathological diagnosis, alongside a review of the current literature.

Journal of Surgical Case ReportsVol. 2026(4)
Leicester Royal Infirmary (GB)
Openalex Percentile: Top 12%
Teratomas and Epidermoid Cysts
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