A Case Report of Preoperative Stereotactic Body Radiotherapy as Part of Multimodal Treatment in Pediatric Extraskeletal Ewing Sarcoma: An Innovative Treatment Strategy

Extraosseous or extraskeletal Ewing sarcoma (E-EWS) is a rare condition that is best managed with a multidisciplinary approach. Radiotherapy (RT) constitutes a cornerstone in the treatment of the EWS tumor group and serves as neoadjuvant or adjuvant therapy, as well as definitive local treatment. Limited information exists on preoperative treatment options for this tumor entity, including stereotactic ablative RT, particularly in the pediatric population. This case report describes a nine-year-old girl with E-EWS located at the left lower costal margin who was successfully treated with multimodal therapy, including preoperative RT.