Dysregulation of Hippo Signaling Pathway as a Convergent Mechanism Underlying Choroid Plexus Defects in Bipolar Disorder
CSF secretion. These findings position the ChP as a genetically and developmentally predisposed to pathology in BD and highlight organoids as a platform for translational discovery in diagnostics and therapeutics.
Authors
- Caihong Qiu
- J H Kim
- Museog Choe
- Ferdi Rıdvan Kiral (ORCID: https://orcid.org/0000-0002-7006-9332)
- Kutlu Kaya (ORCID: https://orcid.org/0000-0002-1826-4659)
- Yue Hu (ORCID: https://orcid.org/0000-0002-9814-0233)
- Michael J Scandura
- Mei Zhong
- Kenneth Ng
- Woosub Yang
Institutions
- Marine Biological Laboratory (US)
- Seoul National University (KR)
- Yale Cancer Center (US)
- Yale University (US)
- Breakthrough (US)
- Yale New Haven Health System (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-04-12
- DOI
- https://doi.org/10.64898/2026.04.10.717745
- Primary Topic
- Hippo pathway signaling and YAP/TAZ
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of Mental Health