Divergent roles of OmpA family proteins in physiology, stress tolerance, and virulence of <i>Elizabethkingia miricola</i>
-5 resulted only in partial attenuation of virulence traits and restricted changes to specific physiological phenotypes. Collectively, these findings establish a functional hierarchy within the OmpA proteins and position OmpA-1 and OmpA-3 as high-priority molecular targets for developing precision therapeutics against this life-threatening, multidrug-resistant pathogen.
Authors
- Zemao Gu (ORCID: https://orcid.org/0000-0002-1278-4610)
- Fangyuan Liu (ORCID: https://orcid.org/0009-0003-4451-8725)
- Fafa He
- Ruixue Hu
Institutions
- Huazhong Agricultural University (CN)
- China Animal Disease Control Center (CN)
- Laboratoire National de Référence (MA)
Publication Details
- Journal
- Virulence
- Published
- 2026-04-11
- DOI
- https://doi.org/10.1080/21505594.2026.2645897
- Primary Topic
- Infections and bacterial resistance
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation