Old Reagent for a Trick in the Stereoselective Hydromethylation of Alkynes Enabled by Cu(I) Photosensitizer Catalysis
diastereoselectivity. This photoredox protocol features Cu(I) photosensitizer catalysis, mild reaction conditions, and sequential C-Si and C-N bond cleavage. Notably, this transformation unveils a novel reactivity mode of an old reagent and represents a rare example of catalytic alkyne hydromethylation.
Authors
- Yin Xu (ORCID: https://orcid.org/0000-0003-0176-9690)
- Yunkui Liu (ORCID: https://orcid.org/0000-0001-8614-458X)
- Xi Chen (ORCID: https://orcid.org/0000-0002-8523-3967)
- Ziwen Huang
- Yun-Fang Yang
- Kun Zhang
Institutions
- Green Chemistry (PL)
- Interface (United Kingdom) (GB)
- Chemical Synthesis Lab (SG)
- Zhejiang University of Technology (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2026-04-11
- DOI
- https://doi.org/10.1021/acs.orglett.6c01090
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China