Tandem Reactivity of Metal−Carbon and Carbon−Silicon Bonds in Mononuclear α‐Silyl Organolithium or Organosodium Complexes Towards CO, CO <sub>2</sub> and Heteroallenes
, or heteroallenes (isocyanates, isothiocyanates, carbodiimides), we report tandem M─C and C─Si bond reactivity, with in-depth mechanistic understanding unveiled by computational reaction pathway studies enabled by the artificial force induced reaction (AFIR) method. By bringing the long-neglected C─Si bond reactivity to the awareness of synthetic chemists, we demonstrate that the C─Si bond should be taken into account in reaction design when using these α-silyl alkyl complexes.
Authors
- Louise Male (ORCID: https://orcid.org/0000-0002-8295-2528)
- Wataru Kanna (ORCID: https://orcid.org/0000-0002-2931-6661)
- Jack M. Hemingway (ORCID: https://orcid.org/0000-0002-3773-4556)
- Hiroki Hayashi (ORCID: https://orcid.org/0000-0003-2081-6886)
- James A. Dawson (ORCID: https://orcid.org/0000-0002-3946-5337)
- Xiaoguang Yang (ORCID: https://orcid.org/0000-0002-9880-3682)
- Nathan Davison (ORCID: https://orcid.org/0009-0006-7315-650X)
- Erli Lu (ORCID: https://orcid.org/0000-0002-0619-5967)
- Paul Gordon Waddell (ORCID: https://orcid.org/0000-0002-7851-7347)
Institutions
- Birmingham City University (GB)
- Hokkaido University (JP)
- University of Birmingham (GB)
- Newcastle University (GB)
Publication Details
- Journal
- Angewandte Chemie International Edition
- Published
- 2026-04-11
- DOI
- https://doi.org/10.1002/anie.8906317
- Primary Topic
- Coordination Chemistry and Organometallics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Leverhulme Trust
- Newcastle University
- University of Birmingham
- Hokkaido University