Coronavirus NSP5 protease cleaves CCDC50 to evade antiviral autophagy

: CCDC50: coiled-coil domain containing 50; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; NBR1: NBR1 autophagy cargo receptor; NSP5: nonstructural protein 5; PDCoV: porcine deltacoronavirus; SQSTM1/p62: sequestosome 1.

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Publication Details

Journal
Autophagy
Published
2026-04-11
DOI
https://doi.org/10.1080/15548627.2026.2658847
Primary Topic
Autophagy in Disease and Therapy
Type
article
Field-Weighted Citation Impact
0.00
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article

Coronavirus NSP5 protease cleaves CCDC50 to evade antiviral autophagy

H. Susan Zhou, Sizhu Suolang, K. Li, Rui Luo et al.
Autophagy
Autophagy in Disease and Therapy
article

Coronavirus NSP5 protease cleaves CCDC50 to evade antiviral autophagy

H. Susan Zhou, Sizhu Suolang, K. Li, Rui Luo, Hongyun Wei, Anan Jongkaewwattana, Wenqiu Yin, Peng Zhou, Hui Jin
article en

Abstract

: CCDC50: coiled-coil domain containing 50; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; NBR1: NBR1 autophagy cargo receptor; NSP5: nonstructural protein 5; PDCoV: porcine deltacoronavirus; SQSTM1/p62: sequestosome 1.

Autophagy
National Science and Technology Development Agency (TH), Huazhong Agricultural University (CN), Center of Hubei Cooperative Innovation for Emissions Trading System (CN)
Good health and well-being
Openalex Percentile: Top 18%
Autophagy in Disease and Therapy
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