Survival analysis and mortality predictors of COVID-19 in Moroccan children: A multicenter study

Objectives: Although COVID-19 in children is benign, it has revealed a critical vulnerability in the neonatal population. This study aimed to identify the mortality predictors and determinants of survival in children affected by COVID-19 in the Marrakech-Safi (RMS) region of Morocco. Methods: This was a retrospective, multicenter cohort study conducted among children hospitalized with COVID-19 between March 2020 and December 2021 in two RMS hospitals. All patients aged under 15 years with confirmed SARS-CoV-2 infection were included; incomplete files, misdiagnoses, and transferred patients were excluded. Overall survival was assessed using the Kaplan-Meier curve, associations were examined with the log-rank test, and predictors were identified using Cox proportional hazards regression models. Results: = 0.005) as major mortality predictors. Conclusion: Implementing rapid intervention and preventive medicine strategies is essential to reducing morbidity and mortality in pediatric populations during future public health emergencies.

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Publication Details

Journal
IJID Regions
Published
2026-04-11
DOI
https://doi.org/10.1016/j.ijregi.2026.100895
Primary Topic
COVID-19 Clinical Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Survival analysis and mortality predictors of COVID-19 in Moroccan children: A multicenter study

Laila Lahlou, Amina Barkat, Hayat Iziki, Souad Yakini et al.
IJID Regions
COVID-19 Clinical Research Studies
article

Survival analysis and mortality predictors of COVID-19 in Moroccan children: A multicenter study

Laila Lahlou, Amina Barkat, Hayat Iziki, Souad Yakini, Hanane El Ghazouani, Omayma Benbrik, Mounia AMANE, Maryama BOU-ISELMANE, El Arbi BOUAITI, Rachida BOUTITI
article en

Abstract

Objectives: Although COVID-19 in children is benign, it has revealed a critical vulnerability in the neonatal population. This study aimed to identify the mortality predictors and determinants of survival in children affected by COVID-19 in the Marrakech-Safi (RMS) region of Morocco. Methods: This was a retrospective, multicenter cohort study conducted among children hospitalized with COVID-19 between March 2020 and December 2021 in two RMS hospitals. All patients aged under 15 years with confirmed SARS-CoV-2 infection were included; incomplete files, misdiagnoses, and transferred patients were excluded. Overall survival was assessed using the Kaplan-Meier curve, associations were examined with the log-rank test, and predictors were identified using Cox proportional hazards regression models. Results: = 0.005) as major mortality predictors. Conclusion: Implementing rapid intervention and preventive medicine strategies is essential to reducing morbidity and mortality in pediatric populations during future public health emergencies.

IJID RegionsVol. 19
Cadi Ayyad University (MA), Mohammed V University (MA), Université Ibn Zohr (MA), Sup de Co Marrakech (MA)
Openalex Percentile: Top 27%
COVID-19 Clinical Research Studies
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