A Rare Presentation of Teratocarcinosarcoma as a Carinal Mass With Review of Literature

Teratocarcinosarcoma (TCS) is a rare, highly aggressive malignant neoplasm composed of epithelial, mesenchymal and neuroectodermal elements, occurring almost exclusively in the sinonasal region. Primary involvement of the tracheobronchial tree or carina has not been previously reported. We describe a 55-year-old male chronic smoker who presented with cough, progressive dyspnea and haemoptysis. Computed tomography revealed a lobulated soft-tissue mass in the distal trachea overhanging the carina, extending into both main bronchi, causing significant airway obstruction. Bronchoscopy demonstrated greater than 80% bilateral luminal occlusion, necessitating urgent endobronchial debulking using rigid bronchoscopy, snare electrocautery, and cryotherapy. Histopathology with immunohistochemistry confirmed teratocarcinosarcoma. Positron emission tomography-computed tomography (PET-CT) showed metabolically active mediastinal and hilar lymph nodes. The patient was treated with chemoradiotherapy. Follow-up bronchoscopy at 6 months showed no recurrence, and the patient remains asymptomatic under surveillance for 4 years. This case represents the first reported carinal presentation of teratocarcinosarcoma, expands the anatomical spectrum of TCS and emphasizes the value of multimodality treatment for sustained disease control.

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Publication Details

Journal
Respirology Case Reports
Published
2026-04-01
DOI
https://doi.org/10.1002/rcr2.70571
Primary Topic
Metastasis and carcinoma case studies
Type
article
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article

A Rare Presentation of Teratocarcinosarcoma as a Carinal Mass With Review of Literature

Binil Salam, Avinash Murugan, Gittwa Vatsaraj Kottangal, Vishnu Gopalakrishnan et al.
Respirology Case Reports
Metastasis and carcinoma case studies
article

A Rare Presentation of Teratocarcinosarcoma as a Carinal Mass With Review of Literature

Binil Salam, Avinash Murugan, Gittwa Vatsaraj Kottangal, Vishnu Gopalakrishnan, Vishnu Suresh, Supriya Ranjith, Pramathakala Mettak
article en

Abstract

Teratocarcinosarcoma (TCS) is a rare, highly aggressive malignant neoplasm composed of epithelial, mesenchymal and neuroectodermal elements, occurring almost exclusively in the sinonasal region. Primary involvement of the tracheobronchial tree or carina has not been previously reported. We describe a 55-year-old male chronic smoker who presented with cough, progressive dyspnea and haemoptysis. Computed tomography revealed a lobulated soft-tissue mass in the distal trachea overhanging the carina, extending into both main bronchi, causing significant airway obstruction. Bronchoscopy demonstrated greater than 80% bilateral luminal occlusion, necessitating urgent endobronchial debulking using rigid bronchoscopy, snare electrocautery, and cryotherapy. Histopathology with immunohistochemistry confirmed teratocarcinosarcoma. Positron emission tomography-computed tomography (PET-CT) showed metabolically active mediastinal and hilar lymph nodes. The patient was treated with chemoradiotherapy. Follow-up bronchoscopy at 6 months showed no recurrence, and the patient remains asymptomatic under surveillance for 4 years. This case represents the first reported carinal presentation of teratocarcinosarcoma, expands the anatomical spectrum of TCS and emphasizes the value of multimodality treatment for sustained disease control.

Respirology Case ReportsVol. 14(4)
ASTER (CA)
Good health and well-being
Openalex Percentile: Top 26%
Metastasis and carcinoma case studies
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