How processing choices effect repeatability in BOLD–CVR imaging
inhalation, breath-hold, and resting-state paradigms, each repeated in a test-retest setup. We found that optimal processing choices varied across paradigms and interacted in non-trivial ways. For example, the inclusion of motion-confounds and the application of temporal filtering require careful consideration, as they can introduce substantial collinearity in the regression model and reduce repeatability. We summarized these findings into practical insights to guide researchers in making sound methodological choices and promote consistency within the field.
Authors
- Gustav Magnusson (ORCID: https://orcid.org/0000-0002-1668-2021)
- Charalampos Georgiopoulos (ORCID: https://orcid.org/0000-0001-8850-3742)
- Gunnar Cedersund (ORCID: https://orcid.org/0000-0001-9386-0568)
- Alex A. Bhogal (ORCID: https://orcid.org/0000-0003-3211-1760)
- Lovisa Tobieson (ORCID: https://orcid.org/0000-0003-2284-846X)
- Anders Tisell (ORCID: https://orcid.org/0000-0003-0928-7282)
- Maria Engström (ORCID: https://orcid.org/0000-0002-2167-2450)
Institutions
- Linköping University (SE)
- Lund University (SE)
- University Medical Center Utrecht (NL)
- CBot (Sweden) (SE)
- Linköping University Hospital (SE)
Publication Details
- Journal
- Journal of Cerebral Blood Flow & Metabolism
- Published
- 2026-04-11
- DOI
- https://doi.org/10.1177/0271678x261420026
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Region Östergötland
- Hjärnfonden
- Linköpings Universitet
- Vetenskapsrådet