Polymicrobial extracellular vesicles reduce the innate immune response of human cystic fibrosis bronchial epithelial cells

currents by CF pHBEC. These studies provide insight into why ETI does not eliminate polymicrobial lung infections and a hyperinflammatory lung environment in pwCF.

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-04-10
DOI
https://doi.org/10.64898/2026.04.09.717493
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
0.00
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article

Polymicrobial extracellular vesicles reduce the innate immune response of human cystic fibrosis bronchial epithelial cells

Prashant Kaushal, Young Ah Goo, Douglas J. Taatjes, Bruce A. Stanton et al.
bioRxiv (Cold Spring Harbor Laboratory)
Bacterial Infections and Vaccines
article

Polymicrobial extracellular vesicles reduce the innate immune response of human cystic fibrosis bronchial epithelial cells

Prashant Kaushal, Young Ah Goo, Douglas J. Taatjes, Bruce A. Stanton, Byoung-Kyu Cho, Carolyn Roche, Alix Ashare, Fabrice Jean-Pierre, Lily A. Charpentier, Roxanna Barnaby, Brad Vietje
article en

Abstract

currents by CF pHBEC. These studies provide insight into why ETI does not eliminate polymicrobial lung infections and a hyperinflammatory lung environment in pwCF.

bioRxiv (Cold Spring Harbor Laboratory)
Dartmouth College (US), University of Vermont (US), James S. McDonnell Foundation (US), Dartmouth–Hitchcock Medical Center (US), Université de Sherbrooke (CA)
Good health and well-being
Openalex Percentile: Top 26%
Bacterial Infections and Vaccines
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Polymicrobial extracellular vesicles reduce the innate immune response of human cystic fibrosis bronchial epithelial cells — Prashant Kaushal, Young Ah Goo, et al. · bioRxiv (Cold Spring Harbor Laboratory) (2026) | TGRS Research Map | TGRS