Hierarchical Reweighting and Network-Control Phenotype: A Bounded Bridge Between the Nature Medicine Psychedelic Mega-Analysis and a Comparative Framework for Biological Cognitive Architectures

This paper is a bounded bridge between the Nature Medicine psychedelic-network mega-analysis and the published comparative framework From Brain Types to Network-Control Phenotypes: A Comparative Framework for Biological Cognitive Architectures. It argues that the psychedelic-network result is best described in terms of selective reconfiguration and reweighting rather than broad collapse, and shows how the comparative language of network-control phenotype helps clarify why that result is theoretically interesting. The contribution is interpretive rather than confirmatory. This release is part of the Reflexive Laboratory series and functions as the bridge paper in the branch Brain Reweighting, Network Control, and Governable Research.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-04-10
DOI
https://doi.org/10.5281/zenodo.19508734
Primary Topic
Psychedelics and Drug Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Hierarchical Reweighting and Network-Control Phenotype: A Bounded Bridge Between the Nature Medicine Psychedelic Mega-Analysis and a Comparative Framework for Biological Cognitive Architectures

Peter Bell
Zenodo (CERN European Organization for Nuclear Research)
Psychedelics and Drug Studies
article

Hierarchical Reweighting and Network-Control Phenotype: A Bounded Bridge Between the Nature Medicine Psychedelic Mega-Analysis and a Comparative Framework for Biological Cognitive Architectures

Peter Bell
article en

Abstract

This paper is a bounded bridge between the Nature Medicine psychedelic-network mega-analysis and the published comparative framework From Brain Types to Network-Control Phenotypes: A Comparative Framework for Biological Cognitive Architectures. It argues that the psychedelic-network result is best described in terms of selective reconfiguration and reweighting rather than broad collapse, and shows how the comparative language of network-control phenotype helps clarify why that result is theoretically interesting. The contribution is interpretive rather than confirmatory. This release is part of the Reflexive Laboratory series and functions as the bridge paper in the branch Brain Reweighting, Network Control, and Governable Research.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 18%
Psychedelics and Drug Studies
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