An Integrative Biophysical and Computational Workflow Uncovers New Allosteric Sites and Modulators of the Human A <sub>2A</sub> Adenosine Receptor

Authors

Matthew T. Eddy (ORCID: https://orcid.org/0000-0002-3349-6212)
Elsa Forcellini
Erika Cecon (ORCID: https://orcid.org/0000-0003-2387-9313)
Ralf Jockers (ORCID: https://orcid.org/0000-0002-4354-1750)
Arka Prabha Ray (ORCID: https://orcid.org/0000-0002-1810-9261)
Tana Tandarić (ORCID: https://orcid.org/0000-0003-1430-5107)
Renaud Prudent
Kerstin Kanonenberg
H. Lemoine
Didier Roche
Hugo Gutiérrez-de-Terán
Alexis Moreno
Naveen Thakur

Institutions

Uppsala University (SE)
Université Paris Cité (FR)
University of Florida (US)
Ruđer Bošković Institute (HR)
National Research Council (LK)
Nanomaterials and Nanotechnology Research Center (ES)
BIOASTER (FR)
Institut Cochin (FR)
Eurofins (France) (FR)

Publication Details

Journal: ACS Chemical Biology
Published: 2026-04-10
DOI: https://doi.org/10.1021/acschembio.6c00003
Primary Topic: Receptor Mechanisms and Signaling
Type: article
Field-Weighted Citation Impact: 0.00

Funders

Ministerio de Ciencia, Innovación y Universidades
Agence Nationale de la Recherche
Institut National de la Santé et de la Recherche Médicale
Fondation pour la Recherche Médicale
Vetenskapsrådet
Centre National de la Recherche Scientifique
National Institute of General Medical Sciences

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article

An Integrative Biophysical and Computational Workflow Uncovers New Allosteric Sites and Modulators of the Human A _2A Adenosine Receptor

Matthew T. Eddy, Elsa Forcellini, Erika Cecon, Ralf Jockers et al.

Apr 10, 2026

ACS Chemical Biology

Receptor Mechanisms and Signaling

article

An Integrative Biophysical and Computational Workflow Uncovers New Allosteric Sites and Modulators of the Human A _2A Adenosine Receptor

Matthew T. Eddy, Elsa Forcellini, Erika Cecon, Ralf Jockers, Arka Prabha Ray, Tana Tandarić, Renaud Prudent, Kerstin Kanonenberg, H. Lemoine, Didier Roche, Hugo Gutiérrez-de-Terán, Alexis Moreno, Naveen Thakur

April 10, 2026article en

Abstract

No abstract available for this paper.

ACS Chemical Biology

Uppsala University (SE), Université Paris Cité (FR), University of Florida (US), Ruđer Bošković Institute (HR), National Research Council (LK), Nanomaterials and Nanotechnology Research Center (ES), BIOASTER (FR), Institut Cochin (FR), Eurofins (France) (FR)

Ministerio de Ciencia, Innovación y Universidades, Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, Fondation pour la Recherche Médicale, Vetenskapsrådet, Centre National de la Recherche Scientifique, National Institute of General Medical Sciences

Openalex Percentile: Top 24%

Receptor Mechanisms and Signaling

DOI Source OpenAlex

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