Berberine Attenuates Glucocorticoid-Induced Bone Loss in Mice: Associated with the Gut Microbiota–Glycerophospholipid Metabolic Axis
was linked to pathway R04864, producing a key glycerophospholipid metabolite positively correlated with bone mass parameters. Overall, these findings suggest that the attenuation of bone loss by BBR may be associated with alterations in the gut microbiota-glycerophospholipid metabolic axis, supporting its potential as a functional food ingredient for bone health.
Authors
- Shengyuan Li (ORCID: https://orcid.org/0000-0003-1665-5434)
- Jimin Zhong
- Xihang Hu (ORCID: https://orcid.org/0009-0004-8314-3740)
- Xinyi Peng
- Min Shi
- Suzhen Chao
- Yang Li
- Bo Liu
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Nanchang University (CN)
- Chinese Center For Disease Control and Prevention (CN)
- State Key Laboratory of Food Science and Technology (CN)
Publication Details
- Journal
- Foods
- Published
- 2026-04-10
- DOI
- https://doi.org/10.3390/foods15081325
- Primary Topic
- Berberine and alkaloids research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China