Correlation between serum triglycerides and prostate cancer risk in Chinese men: a meta-analysis

Background: Epidemiological research presents inconsistent findings on the association between serum triglyceride levels and the risk of developing prostate cancer. However, a systematic review and meta-analysis study on the relationship between triglyceride levels and the risk of prostate cancer in Chinese men are limited. Methods: We explored PubMed, Wanfang, and the China National Knowledge Infrastructure (CNKI) databases to find related retrospective studies on the link between serum triglycerides and prostate cancer. The Newcastle-Ottawa Scale was employed to assess the quality of the study. To compute the pooled odds ratios (OR), a random effects model was utilized. Results: Twelve studies were included, comprising 4732 cases. For prostate cancer, the OR for serum triglyceride levels were 1.03 (95%CI:0.755-1.404, P=0.898). Furthermore, subgroup analysis indicated no link between serum triglyceride levels and prostate cancer risk. Conclusion: We observed no relationship between serum triglyceride and the likelihood of prostate cancer in Chinese men. Due to wide confidence intervals, these results require cautious interpretation and confirmatory replication.