Overexpression of IGF2 Alters the Transcriptional Profile of Goose Skeletal Muscle Satellite Cells
induces a phenotypic shift from myoblasts toward a fibroblast-like state, uncoupling proliferation from differentiation while enhancing fibrogenic identity. This study provides novel insights into IGF2-mediated regulatory mechanisms underlying skeletal muscle development and fibrotic processes.
Authors
- Cui Wang (ORCID: https://orcid.org/0000-0003-2723-5929)
- Yi Liu
- Yunzhou Yang
- Shufang Chen
- Daqian He
Institutions
- Ningbo Academy of Agricultural Sciences (CN)
- Shanghai Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Biomolecules
- Published
- 2026-04-10
- DOI
- https://doi.org/10.3390/biom16040565
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China