Advances in IL–15–Based Cancer Immunotherapy and Divergent Immunological Effects of IL–2 and IL–15 Signaling via the Shared IL–2Rβγ Receptor

T-cell fate decisions, and discusses key opportunities and challenges for translating IL-15-mediated immune enhancement into durable clinical benefit.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-04-10
DOI
https://doi.org/10.3389/fimmu.2026.1791059
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
0.00
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article

Advances in IL–15–Based Cancer Immunotherapy and Divergent Immunological Effects of IL–2 and IL–15 Signaling via the Shared IL–2Rβγ Receptor

Huiquan Gao, Gang Wu, Jinfang Li, Fuxin Zhou et al.
Frontiers in Immunology
Immune Cell Function and Interaction
article

Advances in IL–15–Based Cancer Immunotherapy and Divergent Immunological Effects of IL–2 and IL–15 Signaling via the Shared IL–2Rβγ Receptor

Huiquan Gao, Gang Wu, Jinfang Li, Fuxin Zhou, Wenxin He, Zhixin Zhang, Ziyong Liu, Qinqin Jiang, Shubo Wang, Tao Ma
article en

Abstract

T-cell fate decisions, and discusses key opportunities and challenges for translating IL-15-mediated immune enhancement into durable clinical benefit.

Frontiers in ImmunologyVol. 17
Qingdao University (CN), Tongji University (CN), University of Freiburg (DE), University Medical Center Freiburg (DE), Yuhuangding Hospital (CN), 117th Hospital of People's Liberation Army (CN), 174th hospital of the People's Liberation Army (CN), Affiliated Hospital of Qingdao University (CN), Institut thématique Génétique, génomique et bioinformatique (FR), Weihai Municipal Hospital (CN), Shanghai Pulmonary Hospital (CN), Weihai Maternal and Child Health Hospital (CN)
Openalex Percentile: Top 28%
Immune Cell Function and Interaction
DOIOpen Access PDFOpenAlex
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Advances in IL–15–Based Cancer Immunotherapy and Divergent Immunological Effects of IL–2 and IL–15 Signaling via the Shared IL–2Rβγ Receptor — Huiquan Gao, Gang Wu, et al. · Frontiers in Immunology (2026) | TGRS Research Map | TGRS