Multistage Management of Splenic Flexure Adenocarcinoma in Suspected MUTYH-Associated Polyposis: A Case Report
AIM: -associated polyposis (MAP) and other inherited cancer predisposition syndromes. The purpose of this case report is to highlight management options of incidental MAP diagnosis. CASE PRESENTATION: We report the case of a 41-year-old man presenting to the emergency department with intestinal obstruction due to adenocarcinoma of the splenic flexure, colonic polyposis with rectal sparing, and a significant family history of cancer. RESULTS: After successful endoscopic stenting, a multidisciplinary approach including surgical resection, adjuvant treatment and genetic counseling was carried out. CONCLUSIONS: gene. Absence of rectal involvement made rectal sparing possible in association with close endoscopic follow-up.
Authors
- Noemi Bicelli (ORCID: https://orcid.org/0000-0001-7969-5471)
- Nicola Fazzini (ORCID: https://orcid.org/0000-0002-4701-7534)
- Marco Chiarelli (ORCID: https://orcid.org/0000-0003-3498-0273)
- Andrea Costanzi (ORCID: https://orcid.org/0000-0002-3800-8943)
- Francesca Carissimi (ORCID: https://orcid.org/0000-0002-1647-8397)
- Ilaria Canfora (ORCID: https://orcid.org/0000-0001-8463-7882)
- Alberto Scaini
- Giulia Schievano
- Simone Olmetti
- Giulia Bonfanti
- David Bernasconi
- Humberto Tapia Gomez
Institutions
- University of Milan (IT)
- Alessandro Manzoni Hospital (IT)
- St. Eugenio Hospital (IT)
Publication Details
- Journal
- Annali Italiani di Chirurgia
- Published
- 2026-04-10
- DOI
- https://doi.org/10.62713/aic.4277
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00