ADRENOCORTICAL CARCINOMA IN PREGNANCY. THE FIRST CASE REPORT IN MEXICO AND REVIEW OF THE LITERATURE.

Adrenocortical carcinoma (ACC) in pregnancy is very rare, with fewer than 20 cases reported in the world literature. The most common form of diagnosis is incidental, occurring during imaging studies. However, in pregnancy, gestational hypertension or preeclampsia is one of the signs frequently associated with functional ACC, particularly with cortisol secretion. Histological diagnosis is the gold standard, and in early stages, surgery is the treatment of choice. The prognosis for ACC is extremely poor, but pregnancy-associated ACC is associated with even shorter survival periods. We present a case of ACC in pregnancy that presented with preeclampsia and was diagnosed incidentally. This type of presentation represents a clinical challenge and requires multidisciplinary management to improve the patient's survival.

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Publication Details

Journal
Case Reports in Oncology
Published
2026-04-10
DOI
https://doi.org/10.1159/000551907
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
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article

ADRENOCORTICAL CARCINOMA IN PREGNANCY. THE FIRST CASE REPORT IN MEXICO AND REVIEW OF THE LITERATURE.

Ricardo Fernández-Ferreira, Alejandra Revelles-Martinez, Mariana Hernández-Ramírez, Eunice Vite-Martínez et al.
Case Reports in Oncology
Adrenal and Paraganglionic Tumors
article

ADRENOCORTICAL CARCINOMA IN PREGNANCY. THE FIRST CASE REPORT IN MEXICO AND REVIEW OF THE LITERATURE.

Ricardo Fernández-Ferreira, Alejandra Revelles-Martinez, Mariana Hernández-Ramírez, Eunice Vite-Martínez, Jose Manue Torres-Zazueta, Juan-Pablo Santos-Uscanga, Mauricio-Svein Rodríguez-Mar, Josué-Farid Elías-Delgado, Ximena Flores-Rangel, Abel-Antonio Ricárdez-Espinosa
article en

Abstract

Adrenocortical carcinoma (ACC) in pregnancy is very rare, with fewer than 20 cases reported in the world literature. The most common form of diagnosis is incidental, occurring during imaging studies. However, in pregnancy, gestational hypertension or preeclampsia is one of the signs frequently associated with functional ACC, particularly with cortisol secretion. Histological diagnosis is the gold standard, and in early stages, surgery is the treatment of choice. The prognosis for ACC is extremely poor, but pregnancy-associated ACC is associated with even shorter survival periods. We present a case of ACC in pregnancy that presented with preeclampsia and was diagnosed incidentally. This type of presentation represents a clinical challenge and requires multidisciplinary management to improve the patient's survival.

Case Reports in Oncology
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Adrenal and Paraganglionic Tumors
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