Treatment of Severe Ocular Mpox with Cidofovir and Tecovirimat

Mpox, a reemerging zoonotic disease since 2022, primarily affects the skin; ocular involvement is rarely reported. We present a case of mpox-caused disciform keratitis treated with a combination of cidofovir and tecovirimat. The patient recovered without residual ocular sequelae, suggesting these drugs are an option to treat ocular mpox manifestations.

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Publication Details

Journal
Emerging infectious diseases
Published
2026-04-01
DOI
https://doi.org/10.3201/eid3204.250882
Primary Topic
Poxvirus research and outbreaks
Type
article
Field-Weighted Citation Impact
0.00
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Treatment of Severe Ocular Mpox with Cidofovir and Tecovirimat

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Treatment of Severe Ocular Mpox with Cidofovir and Tecovirimat

Marin Lahouati, Eugénie Mourgues, Valentine Saunier, Charles Cazanave, Sonia Burrel, Rayan Kreidie, Vincent Servant, Xavier Brousse, Luna Fraysse
article en

Abstract

Mpox, a reemerging zoonotic disease since 2022, primarily affects the skin; ocular involvement is rarely reported. We present a case of mpox-caused disciform keratitis treated with a combination of cidofovir and tecovirimat. The patient recovered without residual ocular sequelae, suggesting these drugs are an option to treat ocular mpox manifestations.

Emerging infectious diseasesVol. 32(4)
Good health and well-being
Openalex Percentile: Top 23%
Poxvirus research and outbreaks
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