Differential effects of inspiratory muscle training on diaphragm thickness and exercise tolerance in childhood cancer survivors and non-cancer controls

< 0.05 for all). Thus, we provide preliminary findings suggesting that there might have been differences in the response to training due to cancer treatment-related late effects in CCS. However, these findings should be interpreted with caution given the exploratory nature of our study. Nonetheless, the overall positive benefits of IMT on the respiratory muscles support its potential clinical utility in CCS. Clinical Trial Registration: http://ClinicalTrials.gov NCT06205251 and NCT06230692.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2026-04-10
DOI
https://doi.org/10.3389/fped.2026.1810953
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
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article

Differential effects of inspiratory muscle training on diaphragm thickness and exercise tolerance in childhood cancer survivors and non-cancer controls

Victoria Marchese, S. P. Ho
Frontiers in Pediatrics
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Differential effects of inspiratory muscle training on diaphragm thickness and exercise tolerance in childhood cancer survivors and non-cancer controls

Victoria Marchese, S. P. Ho
article en

Abstract

< 0.05 for all). Thus, we provide preliminary findings suggesting that there might have been differences in the response to training due to cancer treatment-related late effects in CCS. However, these findings should be interpreted with caution given the exploratory nature of our study. Nonetheless, the overall positive benefits of IMT on the respiratory muscles support its potential clinical utility in CCS. Clinical Trial Registration: http://ClinicalTrials.gov NCT06205251 and NCT06230692.

Frontiers in PediatricsVol. 14
University of Maryland, Baltimore (US)
Good health and well-being
Openalex Percentile: Top 26%
Chronic Obstructive Pulmonary Disease (COPD) Research
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