Effectiveness of an Oral Supplementation of Phycocyanin and Palmitoylethanolamide for a Short-Term Prophylaxis of Menstrual Migraine: A Retrospective Observational Study
: In this real-world retrospective study, perimenstrual supplementation with phycocyanin and palmitoylethanolamide was associated with reduced severity, duration, and perimenstrual frequency of menstrual migraine attacks, along with decreased analgesic use, suggesting a safe and potentially beneficial short-term prophylactic strategy for women with menstrual migraine.
Authors
- Loredana Bergandi (ORCID: https://orcid.org/0000-0003-0951-7340)
- Massimo Autunno (ORCID: https://orcid.org/0000-0002-7526-2799)
- Maria Gabriella Saracco (ORCID: https://orcid.org/0000-0001-5641-9079)
- Fabiola Bergandi
- Chiara Benedetto (ORCID: https://orcid.org/0000-0003-1514-4771)
- Gianni Allais (ORCID: https://orcid.org/0000-0002-1946-0109)
- Francesca Silvagno (ORCID: https://orcid.org/0000-0002-8800-9135)
- Luisa Fofi (ORCID: https://orcid.org/0000-0001-7958-5440)
- Florindo D’Onofrio (ORCID: https://orcid.org/0009-0007-1647-3389)
Institutions
- University of Messina (IT)
- Azienda Sanitaria Locale di Asti (IT)
- Azienda Ospedaliera S.Giuseppe Moscati (IT)
- Campus Bio Medico University Hospital (IT)
- University of Turin (IT)
Publication Details
- Journal
- Biomedicines
- Published
- 2026-04-10
- DOI
- https://doi.org/10.3390/biomedicines14040865
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00