Pharmacokinetics, Bioequivalence, and Safety Evaluation of Two Voriconazole Tablets in Healthy Chinese Volunteers
) were determined to be 1.03, 0.98, and 0.97, respectively, under fasting conditions. These values met the established criteria for bioequivalence acceptance. Furthermore, both the test and reference formulations of voriconazole were well tolerated. The findings indicate that the test and reference voriconazole tablets are bioequivalent and possess similar safety profiles in healthy Chinese volunteers.
Authors
- Qin Zuo
- Xiangxiao Deng
- Yinian Fang
- Xingxing Qi
- Qingyan Chen
- Zhen He (ORCID: https://orcid.org/0000-0003-0518-6038)
- Pan Luo (ORCID: https://orcid.org/0000-0002-2620-8622)
- Juan Du
- Hengyi Yu
- Chang Liu
- Xiuhua Ren
- Dongling Zhang
- Yongfang Lei
- Dong Liu
Institutions
- Wuhan Science and Technology Bureau (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Clinical Pharmacology in Drug Development
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1002/cpdd.70058
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00