Efficacy of a Chlorhexidine-Based Oral Prevention Protocol in Reducing Ventilator-Associated Pneumonia in Pediatrics: A Controlled Before-After Study
< .001). Pseudomonas aeruginosa was identified in 57.1% of VAP cases, with polymicrobial infections in 52.4%. All isolates remained antibiotic-susceptible.ConclusionsStructured implementation of an evidence-based VAP bundle may contribute to significant reductions in preventable VAP in pediatric intensive care. While findings are promising, the modest sample size necessitates cautious interpretation and validation through larger multicenter studies.
Authors
- Tony Christian Morena (ORCID: https://orcid.org/0000-0001-6240-8464)
- Orazio Genovese (ORCID: https://orcid.org/0000-0002-1989-1363)
- Giorgia Spinazzola (ORCID: https://orcid.org/0000-0001-8055-5142)
- Enzo Picconi (ORCID: https://orcid.org/0000-0002-1808-0665)
- Marco Piastra (ORCID: https://orcid.org/0000-0002-3144-8970)
- Rita Murri (ORCID: https://orcid.org/0000-0001-9468-5458)
- Federica Tosi (ORCID: https://orcid.org/0000-0001-6146-7411)
- G Conti
- Ivonne Portaccio (ORCID: https://orcid.org/0009-0008-5830-0205)
- Audrey Marie Orr
- Federico De Leonardis
- Ilaria Vitali
- Artiom Noto
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Agostino Gemelli University Polyclinic (IT)
Publication Details
- Journal
- Journal of Intensive Care Medicine
- Published
- 2026-04-10
- DOI
- https://doi.org/10.1177/08850666261440187
- Primary Topic
- Nosocomial Infections in ICU
- Type
- article
- Field-Weighted Citation Impact
- 0.00