Tenerriside A, a Glycoside Variant From <i>Sargassum tenerrimum</i> , Exhibits Potent Angiotensin‐Converting Enzyme (ACE) Inhibitory Activity

, molecular polarizability of 54.47, may enhance recognition at the active enzyme site and lead to the effective inhibition of ACE and improved permeability across intermembrane barriers. Moreover, the low binding energy (-11.95 kcal/mol) and docking score (-14.15 kcal/mol) of Tenerriside A with the key amino acid residues in the ACE active site further support its anti-hypertensive bioactivity.

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Publication Details

Journal
Chemistry & Biodiversity
Published
2026-04-01
DOI
https://doi.org/10.1002/cbdv.202503270
Primary Topic
Seaweed-derived Bioactive Compounds
Type
article
Field-Weighted Citation Impact
0.00
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article

Tenerriside A, a Glycoside Variant From Sargassum tenerrimum , Exhibits Potent Angiotensin‐Converting Enzyme (ACE) Inhibitory Activity

Kajal Chakraborty, Silpa Kunnappilly Paulose
Chemistry & Biodiversity
Seaweed-derived Bioactive Compounds
article

Tenerriside A, a Glycoside Variant From Sargassum tenerrimum , Exhibits Potent Angiotensin‐Converting Enzyme (ACE) Inhibitory Activity

Kajal Chakraborty, Silpa Kunnappilly Paulose
article en

Abstract

, molecular polarizability of 54.47, may enhance recognition at the active enzyme site and lead to the effective inhibition of ACE and improved permeability across intermembrane barriers. Moreover, the low binding energy (-11.95 kcal/mol) and docking score (-14.15 kcal/mol) of Tenerriside A with the key amino acid residues in the ACE active site further support its anti-hypertensive bioactivity.

Chemistry & BiodiversityVol. 23(4)
Cochin University of Science and Technology (IN), Central Marine Fisheries Research Institute (IN)
Life below water
Openalex Percentile: Top 18%
Seaweed-derived Bioactive Compounds
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