Tenerriside A, a Glycoside Variant From <i>Sargassum tenerrimum</i> , Exhibits Potent Angiotensin‐Converting Enzyme (ACE) Inhibitory Activity
, molecular polarizability of 54.47, may enhance recognition at the active enzyme site and lead to the effective inhibition of ACE and improved permeability across intermembrane barriers. Moreover, the low binding energy (-11.95 kcal/mol) and docking score (-14.15 kcal/mol) of Tenerriside A with the key amino acid residues in the ACE active site further support its anti-hypertensive bioactivity.
Authors
- Kajal Chakraborty
- Silpa Kunnappilly Paulose
Institutions
- Cochin University of Science and Technology (IN)
- Central Marine Fisheries Research Institute (IN)
Publication Details
- Journal
- Chemistry & Biodiversity
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1002/cbdv.202503270
- Primary Topic
- Seaweed-derived Bioactive Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00